Article
Role of intracellular carbon metabolism pathways in Shigella flexneri virulence.
Infection and immunity - 1 Jul 2014
Waligora E A, Fisher C R, Hanovice N J, Rodou A, Wyckoff E E, Payne S M
Abstract excerpt
Shigella flexneri, which replicates in the cytoplasm of intestinal epithelial cells, can use the Embden-Meyerhof-Parnas, Entner-Doudoroff, or pentose phosphate pathway for glycolytic carbon metabolism. To determine which of these pathways is used by intracellular S. flexneri, mutants were constructed and tested in a plaque assay for the ability to invade, replicate intracellularly, and spread to adjacent...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
