Article
Peptidomic analysis of the neurolysin-knockout mouse brain.
Journal of proteomics - 5 Dec 2014
Castro Leandro M, Cavalcanti Diogo M L P, Araujo Christiane B, Rioli Vanessa, Icimoto Marcelo Y, Gozzo Fábio C, Juliano Maria, Juliano Luiz, Oliveira Vitor, Ferro Emer S
Abstract excerpt
A large number of intracellular peptides are constantly produced following protein degradation by the proteasome. A few of these peptides function in cell signaling and regulate protein-protein interactions. Neurolysin (Nln) is a structurally defined and biochemically well-characterized endooligopeptidase, and its subcellular distribution and biological activity in the vertebrate brain have been previously...
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