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Article

High prevalence of PfCRT K76T mutation in Plasmodium falciparum isolates in Ghana.

Acta tropica - 1 Aug 2014

Afoakwah Richmond, Boampong Johnson N, Egyir-Yawson Alexander, Nwaefuna Ekene K, Verner Orish N, Asare Kwame K

Abstract excerpt

Plasmodium falciparum has successfully developed resistance to almost all currently used antimalarials. A single nucleotide polymorphism in the P. falciparum chloroquine resistance transporter (Pfcrt) gene at position 76 resulting in a change in coding from lysine to threonine (K76T) has been implicated to be the corner stone of chloroquine resistance. Widespread resistance to chloroquine in endemic regions led...

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Identifiers

PMID: 24727053
DOI: 10.1016/j.actatropica.2014.03.030

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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High prevalence of PfCRT K76T mutation in Plasmodium falciparum isolates in Ghana.PMID 24727053Read ↗

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