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Article

Association of Plasmodium falciparum chloroquine resistance transporter variant T76 with age-related plasma chloroquine levels.

The American journal of tropical medicine and hygiene - 1 Feb 2003

May Jürgen, Meyer Christian G

Abstract excerpt

The mutation leading to the substitution of a threonine (T76) for a lysine at position 76 of the Plasmodium falciparum chloroquine resistance transporter (PfCRT) was genotyped in 100 Nigerian children with asymptomatic parasitemia. Isolates containing both pfcrt variants were found to harbor higher numbers of parasite clones (P < 0.002). The prevalence of the pfcrt T76 variant decreased with age (P < 0.0001) and...

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PMID: 12641402

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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