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Article

HIV-1 mutates to evade IFITM1 restriction.

Virology - 1 Apr 2014

Ding Shilei, Pan Qinghua, Liu Shan-Lu, Liang Chen

Abstract excerpt

Interferon-induced transmembrane (IFITM) proteins inhibit the infection of a wide range of viruses including human immunodeficiency virus type 1 (HIV-1). At present, little is known about how viruses overcome IFITM restriction. In this study, we have utilized HIV-1 as a model and selected IFITM1-resistant viruses after multiple passages of HIV-1 in IFITM1-expressing SupT1 cells. Sequencing the entire viral genome...

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Topics

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Share to Antigens, Differentiation
Share to Cell Line
Share to env Gene Products, Human Immunodeficiency Virus

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Human Immunodeficiency Virus Proteins

Share to Immune Evasion

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Share to Viral Regulatory and Accessory Proteins

Source

Open in PubMed Open full text

Identifiers

PMID: 24725927
DOI: 10.1016/j.virol.2014.01.020
PMCID: PMC4274668

Genes

IFITM1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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