Article
Recognition memory impairments after subcortical white matter stroke in mice.
Stroke - 1 May 2014
Blasi Francesco, Wei Ying, Balkaya Mustafa, Tikka Saara, Mandeville Joseph B, Waeber Christian, Ayata Cenk, Moskowitz Michael A
Abstract excerpt
BACKGROUND AND PURPOSE: Small subcortical white matter infarcts are a common stroke subtype often associated with cognitive deficits. The lack of relevant models confined to white matter has limited the investigation of its pathophysiology. Here, we examine tissue and functional outcome after an ischemic lesion within corpus callosum in wild-type (WT) mice and in mice null for a gene, NOTCH3, linked to white...
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