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Article

The molecular pathogenesis of head and neck squamous cell carcinoma.

The Journal of clinical investigation - 1 Jun 2012

Rothenberg S Michael, Ellisen Leif W

Abstract excerpt

Squamous cell carcinoma of the head and neck (HNSCC) is a relatively common human cancer characterized by high morbidity, high mortality, and few therapeutic options outside of surgery, standard cytotoxic chemotherapy, and radiation. Although the most important risk factors are tobacco use and alcohol consumption, the disease is also linked to infection with high-risk types of human papilloma viruses (HPVs)....

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Source

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Identifiers

PMID: 22833868
DOI: 10.1172/jci59889
PMCID: PMC3589176

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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