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Article

Neuroserpin: a selective inhibitor of tissue-type plasminogen activator in the central nervous system.

Thrombosis and haemostasis - 1 Mar 2004

Yepes Manuel, Lawrence Daniel A

Abstract excerpt

Neuroserpin is a member of the serine proteinase inhibitor (serpin) gene family that reacts preferentially with tissue-type plasminogen activator (tPA) and is primarily localized to neurons in regions of the brain where tPA is also found. Outside of the central nervous system (CNS) tPA is predominantly found in the blood where its primary function is as a thrombolytic enzyme. However, tPA is also expressed within...

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Identifiers

PMID: 14983220
DOI: 10.1160/TH03-12-0766

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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