Effects of type 1 and type 2 diabetes on the pharmacokinetics of tramadol enantiomers in patients with neuropathic pain phenotyped as cytochrome P450 2D6 extensive metabolizers.

Abstract excerpt

OBJECTIVES: The aim of this study was to evaluate the influence of poorly controlled type 1 (T1DM) and type 2 diabetes mellitus (T2DM) on the pharmacokinetics and metabolism of tramadol enantiomers in patients with neuropathic pain. METHODS: Nondiabetic patients (control group, n = 12), patients...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Analgesics, Opioid
• Share to Area Under Curve
• Share to Blood Glucose