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Article

miR-663 Suppresses Oncogenic Function of CXCR4 in Glioblastoma

28 May 2015

Abstract excerpt

PURPOSE: To identify the miRNA regulators of C-X-C motif chemokine receptor 4 (CXCR4) and the underlying mechanism as well as the therapeutic and prognostic values in human glioblastoma (GBM). EXPERIMENTAL DESIGN: miRNA profile analyses and bioinformatics predictions were used to identify the mediators of CXCR4, which were confirmed by luciferase reporter assay, Western blot assay and immunohistochemistry. The...

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PMID: 26023083
DOI: 10.1158/1078-0432.ccr-14-2807

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