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Article

Prevention of CpG-induced pregnancy disruption by adoptive transfer of in vitro-induced regulatory T cells.

PloS one - 1 Jan 2014

Lin Yi, Liu Xiaorui, Shan Bin, Wu Ji, Sharma Surendra, Sun Yun

Abstract excerpt

OBJECTIVE: To elucidate the mechanism by which embryo-resorption and preterm birth were enhanced by pathogenic CpG motif and to develop a counter strategy for normal pregnancy outcome. METHODS: This is an animal model-based study. In pregnant nonobese diabetic (NOD) mice and wild-type (WT) mice in the same strain background, an infection was mimicked by toll-like receptor 9 (TLR9) activation through...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Mice, Inbred NOD

Share to Oligodeoxyribonucleotides

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Source

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Identifiers

PMID: 24714634
DOI: 10.1371/journal.pone.0094702
PMCID: PMC3979847

Genes

TLR9

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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