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Article

Adoptive transfer of Tregs: A novel strategy for cell-based immunotherapy in spontaneous abortion: Lessons from experimental models.

International immunopharmacology - 1 Jan 2021

Mohammadi Sasan, Abdollahi Elham, Nezamnia Maria, Esmaeili Seyed-Alireza, Tavasolian Fataneh, Sathyapalan Thozhukat, Sahebkar Amirhossein

Abstract excerpt

Since half of the genes are inherited from the paternal side, the maternal immune system has to tolerate the presence of foreign paternal antigens. Regulatory T cells facilitate the development and maintenance of peripheral tissue tolerance of the fetus during pregnancy. Reduction in regulatory T cells is associated with complications of pregnancy, including spontaneous abortion. Recent studies in mouse models...

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Source

Identifiers

PMID: 33278746
DOI: 10.1016/j.intimp.2020.107195

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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