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Article

Regulatory T cells protect from autoimmune arthritis during pregnancy

18 Oct 2011

Abstract excerpt

Pregnancy frequently has a beneficial effect on the autoimmune disease Rheumatoid Arthritis, ranging from improvement in clinical symptoms to complete remission. Despite decades of study, a mechanistic explanation remains elusive. Here, we demonstrate that an analogous pregnancy-induced remission can be observed in a mouse model of arthritis. We demonstrate that during pregnancy mice are protected from...

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PMID: 22004905
DOI: 10.1016/j.jaut.2011.09.007

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