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Article

Adjuvant-specific regulation of long-term antibody responses by ZBTB20.

The Journal of experimental medicine - 5 May 2014

Wang Yinan, Bhattacharya Deepta

Abstract excerpt

The duration of antibody production by long-lived plasma cells varies with the type of immunization, but the basis for these differences is unknown. We demonstrate that plasma cells formed in response to the same immunogen engage distinct survival programs depending on the adjuvant. After alum-adjuvanted immunization, antigen-specific bone marrow plasma cells deficient in the transcription factor ZBTB20 failed to...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 24711582
DOI: 10.1084/jem.20131821
PMCID: PMC4010912

Genes

ZBTB20
BCL2
MCL1
TLR2
TLR4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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