Article

Pan-Cancer Genetic Profiles of Mitotic DNA Integrity Checkpoint Protein Kinases

2024-11-15

Abstract excerpt

<h4>ABSTRACT</h4> <h4>BACKGROUND</h4> The mitotic DNA integrity checkpoint signaling pathway is potentially involved in cancers that regulate genomic stability where protein kinases play a pivotal role. 16 total protein kinase genes are involved in this pathway: ATM, BRSK1, CDK1, CDK2, CHEK1, CHEK2, MAP3K20, NEK11, PLK1, PLK2, PLK3, PRKDC, STK33, TAOK1, TAOK2, and TAOK3. This study aims to provide pan-cancer pro...

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Literature Corpus work: 41389956-4a4d-5bbb-a3c0-bcbed88ff0c7
DOI: 10.1101/2024.11.15.623822

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