Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Links between nucleolar activity, rDNA stability, aneuploidy and chronological aging in the yeast Saccharomyces cerevisiae.

Biogerontology - 1 Jun 2014

Lewinska Anna, Miedziak Beata, Kulak Klaudia, Molon Mateusz, Wnuk Maciej

Abstract excerpt

The nucleolus is speculated to be a regulator of cellular senescence in numerous biological systems (Guarente, Genes Dev 11(19):2449-2455, 1997; Johnson et al., Curr Opin Cell Biol 10(3):332-338, 1998). In the budding yeast Saccharomyces cerevisiae, alterations in nucleolar architecture, the redistribution of nucleolar protein and the accumulation of extrachromosomal ribosomal DNA circles (ERCs) during...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aneuploidy
Share to Cell Nucleolus
Share to DNA, Ribosomal

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Membrane Potential, Mitochondrial

Share to RNA-Binding Proteins

Share to Shelterin Complex

Share to Silent Information Regulator Proteins, Saccharomyces cerevisiae

Share to Telomere-Binding Proteins

Source

Open in PubMed Open full text

Identifiers

PMID: 24711086
DOI: 10.1007/s10522-014-9499-y
PMCID: PMC4019837

Genes

BUB1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Links between nucleolar activity, rDNA stability, aneuploidy and chronological aging in the yeast Saccharomyces cerevisiae.PMID 24711086Read ↗

Mitotic Dysfunction Associated with Aging Hallmarks.Semantic proximity Read ↗

Reproductive potential and instability of the rDNA region of the Saccharomyces cerevisiae yeast: Common or separate mechanisms of regulation?Semantic proximity Read ↗

Aneuploidy in health, disease, and agingSemantic proximity Read ↗

Recent advances in the nucleolar responses to DNA double-strand breaksSemantic proximity Read ↗

Link between aging and the nucleolus.Semantic proximity Read ↗

BubR1 kinase: protection against aneuploidy and premature aging.Semantic proximity Read ↗

Premature aging in aneuploid yeast is caused in part by aneuploidy-induced defects in Ribosome Quality ControlSemantic proximity Read ↗

The Nucleolus: In Genome Maintenance and Repair.Semantic proximity Read ↗

Hydrogen peroxide prolongs mitotic arrest in a dose dependent manner and independently of the spindle assembly checkpoint activity in Saccharomyces cerevisiae.Semantic proximity Read ↗

Dynamics of age-related catastrophic mitotic failures and recovery in yeastSemantic proximity Read ↗

Changes in Chromatin Organization Eradicate Cellular Stress Resilience to UVA/B Light and Induce Premature Aging.Semantic proximity Read ↗

The anaphase promoting complex regulates yeast lifespan and rDNA stability by targeting Fob1 for degradation.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.