Article
Links between nucleolar activity, rDNA stability, aneuploidy and chronological aging in the yeast Saccharomyces cerevisiae.
Biogerontology - 1 Jun 2014
Lewinska Anna, Miedziak Beata, Kulak Klaudia, Molon Mateusz, Wnuk Maciej
Abstract excerpt
The nucleolus is speculated to be a regulator of cellular senescence in numerous biological systems (Guarente, Genes Dev 11(19):2449-2455, 1997; Johnson et al., Curr Opin Cell Biol 10(3):332-338, 1998). In the budding yeast Saccharomyces cerevisiae, alterations in nucleolar architecture, the redi...
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