Article
Value of dopachrome tautomerase detection in the assessment of melanocytic tumors.
Melanoma research - 1 Jun 2014
Filimon Anca, Zurac Sabina A, Milac Adina L, Sima Livia E, Petrescu Stefana M, Negroiu Gabriela
Abstract excerpt
Dopachrome tautomerase (DCT) and tyrosinase (Tyr) are melanogenic enzymes and structurally related melanosomal proteins. The present study investigates DCT expression comparatively with Tyr, the most tested melanoma biomarker, aiming to evaluate DCT potential in the assessment of melanocytic tumors and gain insights into the molecular and pathological characterization of DCT-phenotype in tumor progression. DCT...
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