Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Clinical and pathologic findings of Spitz nevi and atypical Spitz tumors with ALK fusions.

The American journal of surgical pathology - 1 Jul 2014

Busam Klaus J, Kutzner Heinz, Cerroni Lorenzo, Wiesner Thomas

Abstract excerpt

Spitz tumors represent a group of melanocytic neoplasms that typically affect young individuals. Microscopically, the lesions are composed of cytologically distinct spindle and epithelioid melanocytes, with a range in the architectural display or the cells, their nuclear features, and secondary epidermal or stromal changes. Recently, kinase fusions have been documented in a subset of Spitz tumors, but there is...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Anaplastic Lymphoma Kinase
Share to Dynactin Complex

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Fusion

Share to Gene Rearrangement

Share to Lymphatic Metastasis

Share to Microtubule-Associated Proteins

Share to Receptor Protein-Tyrosine Kinases

Share to Tropomyosin

Source

Open in PubMed Open full text

Identifiers

PMID: 24698967
DOI: 10.1097/PAS.0000000000000187
PMCID: PMC5042334

Genes

ALK
DCTN1
TPM3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Clinical and pathologic findings of Spitz nevi and atypical Spitz tumors with ALK fusions.PMID 24698967Read ↗

A Clinicopathological Study of 29 Spitzoid Melanocytic Lesions With ALK Fusions, Including Novel Fusion Variants, Accompanied by Fluorescence In Situ Hybridization Analysis for Chromosomal Copy Number Changes, and Both TERT Promoter and Next-Generation Sequencing Mutation Analysis.Semantic proximity Read ↗

Benign and Intermediate-grade Melanocytic Tumors With BRAF Mutations and Spitzoid Morphology: A Subset of Melanocytic Neoplasms Distinct From Melanoma.Semantic proximity Read ↗

A Comparison of Morphologic and Molecular Features of BRAF, ALK, and NTRK1 Fusion Spitzoid Neoplasms.Semantic proximity Read ↗

Spitz Tumors With ROS1 Fusions: A Clinicopathological Study of 6 Cases, Including FISH for Chromosomal Copy Number Alterations and Mutation Analysis Using Next-Generation SequencingSemantic proximity Read ↗

The Extended Spectrum of Morphologic and Molecular Findings in ALK Fusion Spitz Neoplasms : A Study of 144 Cases.Semantic proximity Read ↗

Prevalence of ALK gene alterations among the spectrum of plexiform spitzoid lesions.Semantic proximity Read ↗

Kinase Fusions in Spitz Melanocytic Tumors: The Past, the Present, and the FutureSemantic proximity Read ↗

Clinical, Morphologic, and Molecular Features of Benign and Intermediate-grade Melanocytic Tumors With Activating Mutations in MAP2K1.Semantic proximity Read ↗

Toward a Molecular-Genetic Classification of Spitzoid Neoplasms.Semantic proximity Read ↗

Spitz nevus with EHBP1‐ALK fusion and distinctive membranous localization of ALKSemantic proximity Read ↗

Spitz melanocytic neoplasms with MLPH::ALK fusions: Report of two cases with previously unreported features and literature reviewSemantic proximity Read ↗

BRAF fusion Spitz neoplasms; clinical morphological, and genomic findings in six cases.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.