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Spitz melanocytic neoplasms with MLPH::ALK fusions: Report of two cases with previously unreported features and literature review

5 Mar 2024

Abstract excerpt

ALK-fused Spitz melanocytic neoplasms are a distinct subgroup of melanocytic lesions exhibiting unique histopathologic characteristics. These lesions often manifest as exophytic or polypoid tumors, characterized by fusiform-to-epithelioid melanocytes arranged in a nested, fascicular, or plexiform growth pattern. Several fusion partners of the ALK gene have been identified in spitzoid melanocytic neoplasms, with...

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PMID: 38444194
DOI: 10.1111/cup.14605

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