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Article

A Comparison of Morphologic and Molecular Features of BRAF, ALK, and NTRK1 Fusion Spitzoid Neoplasms.

The American journal of surgical pathology - 1 Apr 2017

Amin Sapna M, Haugh Alexandra M, Lee Christina Y, Zhang Bin, Bubley Jeffrey A, Merkel Emily A, Verzì Anna Elisa, Gerami Pedram

Abstract excerpt

Recent studies have identified translocations involving the kinase domains of ALK, NTRK1, BRAF, RET, and ROS in spitzoid neoplasms. Subsequent studies have also characterized morphologic features corresponding to ALK and NTRK1 translocations. In this study, we sought to further compare morphologic features across a range of 49 genetically defined spitzoid neoplasms with ALK, NTRK1, BRAF, or RET fusions to...

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Share to Anaplastic Lymphoma Kinase
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Proto-Oncogene Proteins c-ret

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Share to Receptor, trkA

Share to Translocation, Genetic

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Source

Identifiers

PMID: 27776007
DOI: 10.1097/PAS.0000000000000761

Genes

BRAF
ALK
NTRK1
RET

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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