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Spitz nevus with EHBP1‐ALK fusion and distinctive membranous localization of ALK

3 Feb 2022

Abstract excerpt

ALK rearrangements define a histopathologically distinctive yet diverse subset of Spitz tumors characterized by fusiform to epithelioid melanocytes with frequent fascicular growth and ALK overexpression. Molecularly, these tumors are characterized by fusions between ALK and a variety of gene partners, most commonly TPM3 and DCTN1. We describe an unusual case of a Spitz nevus occurring in a 13-year-old female that...

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Cancer Genomics and Diagnostics
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Salivary Gland Tumors Diagnosis and Treatment

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PMID: 35113459
DOI: 10.1111/cup.14209

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