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Article

Enhanced invasion of lung adenocarcinoma cells after co-culture with THP-1-derived macrophages via the induction of EMT by IL-6.

Immunology letters - 1 Jul 2014

Dehai Che, Bo Pan, Qiang Tian, Lihua Shang, Fang Liu, Shi Jin, Jingyan Cao, Yan Yu, Guangbin Wang, Zhenjun Yuan

Abstract excerpt

Lung cancer is the leading cause of cancer mortality worldwide, and the cause of death is metastasis. The epithelial-to-mesenchymal transition (EMT) plays a key role in the process of metastasis. Macrophages within the lung cancer microenvironment release cytokines, such as interleukin-6 (IL-6),...

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Identifiers

PMID: 24698728
DOI: 10.1016/j.imlet.2014.03.004

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-24698728-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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