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Article

A distinct role for interleukin-6 as a major mediator of cellular adjustment to an altered culture condition.

Journal of cellular biochemistry - 1 Nov 2015

Son Hwa-Kyung, Park Iha, Kim Jue Young, Kim Do Kyeong, Illeperuma Rasika P, Bae Jung Yoon, Lee Doo Young, Oh Eun-Sang, Jung Da-Woon, Williams Darren R, Kim Jin

Abstract excerpt

Tissue microenvironment adjusts biological properties of different cells by modulating signaling pathways and cell to cell interactions. This study showed that epithelial-mesenchymal transition (EMT)/ mesenchymal-epithelial transition (MET) can be modulated by altering culture conditions. HPV E6/E7-transfected immortalized oral keratinocytes (IHOK) cultured in different media displayed reversible EMT/MET...

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Identifiers

PMID: 25939389
DOI: 10.1002/jcb.25200
PMCID: PMC4832257

Genes

MET

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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