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Gram-negative bacterial infection increases lung cancer metastasis via Toll-like receptor activation and increased cancer cell proliferation post-tumor adhesion

2021-09-16

Abstract excerpt

<h4>Background</h4> Lung cancer is a leading cause of death partially due to high recurrence rates after surgical resection. Clinical data suggest that post-operative infections may increase the risk of recurrence. Our previous work indicated that increased adhesion of circulating tumors in the context of infection is partially responsible for this phenotype. However, cancer metastasis is a multi-step process, an...

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Literature Corpus work
d1439ac3-b329-58fd-b9b2-4ac0c310d4ad
DOI
10.1101/2021.09.15.460508
Open publication

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Gram-negative bacterial infection increases lung cancer metastasis via Toll-like receptor activation and increased cancer cell proliferation post-tumor adhesionDOI 10.1101/2021.09.15.460508
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