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Regulation of antimycin biosynthesis by the orphan ECF RNA polymerase sigma factor <b>σ</b> <sup> <b>AntA</b> </sup>

6 Feb 2014

Abstract excerpt

Antimycins are an extended family of depsipeptides that are made by filamentous actinomycete bacteria and were first isolated more than 60 years ago. Recently, antimycins have attracted renewed interest because of their activities against the anti-apoptotic machineries inside human cells which could make them promising anti-cancer compounds. The biosynthetic pathway for antimycins was recently characterised but...

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PMID: 24688837
DOI: 10.7717/peerj.253

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