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Biotechnological production and application of the antibiotic pimaricin: biosynthesis and its regulation

29 Oct 2015

Abstract excerpt

Pimaricin (natamycin) is a small polyene macrolide antibiotic used worldwide. This efficient antimycotic and antiprotozoal agent, produced by several soil bacterial species of the genus Streptomyces, has found application in human therapy, in the food and beverage industries and as pesticide. It displays a broad spectrum of activity, targeting ergosterol but bearing a particular mode of action different to other...

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PMID: 26512010
DOI: 10.1007/s00253-015-7077-0

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