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Article

Is susceptibility locus for lung cancer in the 15q25 nicotinic acetylcholine receptor gene cluster CHRNA5-A3-B4 associated with risk of gastric cancer?

Medical oncology (Northwood, London, England) - 1 Jan 2013

Wu Haijian, Wang Yang, Wang Shikun, Jiang Man, Wang Cuihong, Fu Weijiang, Hu Likuan

Abstract excerpt

An association between common variants in the 15q25 nicotinic acetylcholine receptor (nAChR) gene cluster CHRNA5-A3-B4 (responsible for encoding nAChR subunits) and lung cancer risk has recently been reported in both Caucasian and Chinese population. Cigarette smoking is one of the major risk factors for both lung and gastric cancer. Moreover, nAChR plays an important role in cigarette smoke-related lung...

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PMID: 23576140
DOI: 10.1007/s12032-013-0576-x

Genes

CHRNA5

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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