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Article

Dm-myb mutant lethality in Drosophila is dependent upon mip130: positive and negative regulation of DNA replication.

Genes & development - 15 Jul 2004

Beall Eileen L, Bell Maren, Georlette Daphne, Botchan Michael R

Abstract excerpt

Gene amplification at the chorion loci in Drosophila ovarian follicle cells is a model for the developmental regulation of DNA replication. Previously, we showed that the Drosophila homolog of the Myb oncoprotein family (DmMyb) is tightly associated with four additional proteins and that DmMyb is required for this replication-mediated amplification. Here we used targeted mutagenesis to generate a mutant in the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 15256498
DOI: 10.1101/gad.1206604
PMCID: PMC478189

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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