Article
Toll-like receptor 3 polymorphism rs3775291 is not associated with choroidal neovascularization or polypoidal choroidal vasculopathy in Chinese subjects.
Ophthalmic research - 1 Jan 2011
Sng Chelvin C A, Cackett Peter D, Yeo Ian Y, Thalamuthu Anbupalam, Venkatraman Anandalakshmi, Venkataraman Divya, Koh Adrian H, Tai E-Shyong, Wong Tien Y, Aung Tin, Vithana Eranga N
Abstract excerpt
BACKGROUND/AIMS: Age-related macular degeneration (AMD) is a leading cause of visual impairment. A single-nucleotide polymorphism (SNP; rs3775291) in the Toll-like receptor 3 (TLR3) gene has recently been implicated in the pathogenesis of AMD in Caucasian populations. The aim of this study was to examine this association in Chinese persons with choroidal neovascularization (CNV) secondary to AMD and polypoidal...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.