Article
β-Defensin 1 haplotype associated with postoperative endophthalmitis.
Acta ophthalmologica - 1 Nov 2010
Carter James G, West Stephanie K, Painter Sally, Haynes Richard J, Churchill Amanda J
Abstract excerpt
PURPOSE: Endophthalmitis is a rare but sight-threatening complication of intraocular surgery. β-Defensins are antimicrobial peptides that appear to be important components of the ocular immune response. We propose that variation in defensin genes may alter susceptibility to endophthalmitis. METHODS: Post-cataract endophthalmitis patients (n = 28) and post-cataract controls (n = 75) were recruited and DNA samples...
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