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Article

Immune defense single nucleotide polymorphisms and recruitment strategies associated with contact lens keratitis.

Ophthalmology - 1 Oct 2012

Carnt Nicole A, Willcox Mark D P, Hau Scott, Keay Lisa, Dart John K G, Chakrabarti Subhabrata, Stapleton Fiona

Abstract excerpt

PURPOSE: To determine the association of single nucleotide polymorphisms (SNPs) of defensin 1B and toll-like receptor 4 with contact lens keratitis susceptibility and severity, and to understand the factors that influence study participation. DESIGN: Retrospective, case-control study. PARTICIPANTS: Ninety cases of keratitis and 185 controls recruited from studies conducted at Moorfields Eye Hospital and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 22809755
DOI: 10.1016/j.ophtha.2012.05.020

Genes

DEFB1
TLR4

Variants

rs1799946

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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