Article
Association between common genetic variants of α2A-, α2B- and α2C-adrenoceptors and the risk of silent brain infarction.
Molecular medicine reports - 1 Jun 2014
Kim Jung O, Jeon Young Joo, Kim Ok Joon, Oh Seung Hun, Kim Hyun Sook, Shin Byoung Soo, Oh Doyeun, Kim Eo Jin, Cho Yun Kyung, Kim Nam Keun
Abstract excerpt
Silent brain infarction (SBI) is an asymptomatic cerebrovascular disorder. The aim of the present study was to investigate the association between adrenoceptor-α2 (ADRA2) gene polymorphisms and SBI. A total of 361 patients with SBI and 467 healthy control subjects were examined. The polymerase chain reaction was performed to genotype the ADRA2A 1780G>A, ADRA2B 301-303 insertion/deletion (I/D) and ADRA2C...
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