Article
Beta2-adrenergic receptor gene polymorphisms and risk of ischemic stroke.
American journal of hypertension - 1 Jun 2007
Stanzione Rosita, Di Angelantonio Emanuele, Evangelista Anna, Barbato Daniela, Marchitti Simona, Zanda Bastianina, Pirisi Angelo, Quarta Giovanni, Volpe Massimo, Rubattu Speranza
Abstract excerpt
BACKGROUND: Beta2-adrenergic receptors (beta2-AR) mediate vasorelaxation in response to adrenergic agents. Genetic polymorphisms of beta2-AR were implicated in various cardiovascular and noncardiovascular traits. METHODS: We tested the role of the beta2AR-16 and beta2AR-27 gene variants in the susceptibility to the development of ischemic stroke in a genetically homogenous and clinically well-characterized...
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