Article
Association of Fcgamma receptor type 2A and 3A genotypes with rheumatoid arthritis in Chinese population.
Pharmacogenomics - 1 Feb 2017
Sun Yining, Mo Lingfei, Feng Xiuyuan, Yang Dongmei, Tan Taochao, Zeng Lingxia, Hui Lingyun, Wang Yawen, Liu Cheng, He Lan
Abstract excerpt
AIM: SNPs of FcγRs were implicated in pathogenesis of rheumatoid arthritis (RA) and treatment efficacy of TNF inhibitors (TNFi). This study aims to investigate the associations of FcγRIIa and FcγRIIIa genotypes with autoantibody production and treatment response to TNFi in Chinese patients with RA. PATIENTS & METHODS: FcγRIIa and FcγRIIIa polymorphisms were genotyped in 158 RA patients. Response to TNFi was...
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