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Article

Evaluation of customised lineage-specific sets of MIRU-VNTR loci for genotyping Mycobacterium tuberculosis complex isolates in Ghana.

PloS one - 1 Jan 2014

Asante-Poku Adwoa, Nyaho Michael Selasi, Borrell Sonia, Comas Iñaki, Gagneux Sebastien, Yeboah-Manu Dorothy

Abstract excerpt

BACKGROUND: Different combinations of variable number of tandem repeat (VNTR) loci have been proposed for genotyping Mycobacterium tuberculosis complex (MTBC). Existing VNTR schemes show different discriminatory capacity among the six human MTBC lineages. Here, we evaluated the discriminatory power of a "customized MIRU12" loci format proposed previously by Comas et al. based on the standard 24 loci defined by...

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PMID: 24667333
DOI: 10.1371/journal.pone.0092675
PMCID: PMC3965448

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