Article
Evaluation of the new advanced 15-loci MIRU-VNTR genotyping tool in Mycobacterium tuberculosis molecular epidemiology studies.
BMC microbiology - 24 Feb 2008
Alonso-Rodríguez Noelia, Martínez-Lirola Miguel, Herránz Marta, Sanchez-Benitez Marisa, Barroso Pilar, Bouza Emilio, García de Viedma Darío
Abstract excerpt
BACKGROUND: During the last few years, PCR-based methods have been developed to simplify and reduce the time required for genotyping Mycobacterium tuberculosis (MTB) by standard approaches based on IS6110-Restriction Fragment Length Polymorphism (RFLP). Of these, MIRU-12-VNTR (Mycobacterial interspersed repetitive units- variable number of tandem repeats) (MIRU-12) has been considered a good alternative....
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