Article
Evaluation of spoligotyping, SNPs and customised MIRU-VNTR combination for genotyping Mycobacterium tuberculosis clinical isolates in Madagascar.
PloS one - 1 Jan 2017
Rasoahanitralisoa Rondroarivelo, Rakotosamimanana Niaina, Stucki David, Sola Christophe, Gagneux Sebastien, Rasolofo Razanamparany Voahangy
Abstract excerpt
BACKGROUND: Combining different molecular typing methods for Mycobacterium tuberculosis complex (MTBC) can be a powerful tool for molecular epidemiology-based investigation of TB. However, the current standard method that provides high discriminatory power for such a combination, mycobacterial interspersed repetitive units-variable numbers of tandem repeats typing (MIRU-VNTR), is laborious, time-consuming and...
Topics
- Genotype
- Madagascar
- Minisatellite Repeats
- Mycobacterium tuberculosis
- Polymorphism, Single Nucleotide
