Article
Developing customized stepwise MIRU-VNTR typing for tuberculosis surveillance in Georgia.
PloS one - 1 Jan 2022
Maghradze Nino, Jugheli Levan, Borrell Sonia, Tukvadze Nestani, Kempker Russell R, Blumberg Henry M, Gagneux Sebastien
Abstract excerpt
INTRODUCTION: Mycobacterial Interspersed Repetitive Units-Variable Tandem Repeats (MIRU-VNTR) typing has been widely used for molecular epidemiological studies of tuberculosis (TB). However, genotyping tools for Mycobacterium tuberculosis (Mtb) may be limiting in some settings due to high cost and workload. In this study developed a customized stepwise MIRU-VNTR typing that prioritizes high discriminatory loci...
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