Article
Cys327Cys polymorphism of the PAPP-A gene (pregnancy associated plasma protein A) is related to mortality of long term hemodialysis patients.
Clinical biochemistry - 1 May 2014
Kalousová Marta, Jáchymová Marie, Muravská Alexandra, Kuběna Aleš A, Dusilová-Sulková Sylvie, Tesař Vladimír, Zima Tomáš
Abstract excerpt
OBJECTIVES: PAPP-A is an independent mortality predictor of long term hemodialysis patients and a prognostic marker of acute coronary syndrome in general population. Cys327Cys PAPP-A polymorphism (SNP) (rs12375498) was found to be of significance in preeclampsia and the C allele of the PAPP-A C/G SNP (rs13290387) was defined as an independent risk factor for acute myocardial infarction. The aim of the study was...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
