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Article

[The functional study of antithrombin L99 mutation].

Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi - 1 Mar 2014

Yu Tingting, Dai Jing, Ding Qiulan, Fu Qihua, Wang Xuefeng

Abstract excerpt

OBJECTIVE: To study the molecular mechanisms of inherited antithrombin (AT) deficiency caused by AT L99 mutation. METHODS: Wild type (WT), L99V, L99A, L99I and L99S AT were purified from drosophila expression system. The binding capacity of AT and the low molecular weight heparin sodium was analyzed by the heparin binding assay. Surface plasmon resonance (SPR) was used to detect the binding ability of AT to...

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PMID: 24666482
DOI: 10.3760/cma.j.issn.0253-2727.2014.03.003

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SPR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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