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[Study on the molecular mechanism of antithrombin gene C2759T (Leu99Phe) mutation causing antithrombin deficiency].

Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi - 1 Mar 2005

Fu Qi-hua, Wang Wen-bin, Ding Qiu-lan, Zhou Rong-fu, Wu Wen-man, Hu Yi-qun, Wang Xue-feng, Yan Li-xing, Wang Zhen-yi, Wang Hong-li

Abstract excerpt

OBJECTIVE: To study the molecular mechanism of antithrombin (AT) gene C2759T (Leu99Phe) mutation causing AT deficiency. METHODS: A mutated AT cDNA expression plasmid ATM2759 was constructed by mega-primer method. ATM2759 and wild type AT cDNA expression plasmid ATN were transfected into COS7 cells or CHO cells by using Superfect reagent respectively for in vitro expression study and immunofluorescence assay....

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PMID: 15946526

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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