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Article

High-resolution melt as a screening method in autosomal dominant polycystic kidney disease (ADPKD).

Journal of clinical laboratory analysis - 1 Jul 2014

Virzì Grazia Maria, Bruson Alice, Corradi Valentina, Gastaldon Fiorella, de Cal Massimo, Donà Marta, Cruz Dinna N, Clementi Maurizio, Ronco Claudio

Abstract excerpt

BACKGROUND: Autosomal dominant polycystic kidney disease (ADPKD) is an inherited condition caused by PKD1 and PKD2 mutations. Complete analysis of both genes is typically required in each patient. In this study, we explored the utility of High-Resolution Melt (HRM) as a tool for mutation analysis...

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Source

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Identifiers

PMID: 24658975
DOI: 10.1002/jcla.21689
PMCID: PMC6807430

Genes

PKD2
PKD1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-24658975-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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