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Article

GeMes, clusters of DNA methylation under genetic control, can inform genetic and epigenetic analysis of disease.

American journal of human genetics - 3 Apr 2014

Liu Yun, Li Xin, Aryee Martin J, Ekström Tomas J, Padyukov Leonid, Klareskog Lars, Vandiver Amy, Moore Ann Zenobia, Tanaka Toshiko, Ferrucci Luigi, Fallin M Daniele, Feinberg Andrew P

Abstract excerpt

Epigenetic marks such as DNA methylation have generated great interest in the study of human disease. However, studies of DNA methylation have not established population-epigenetics principles to guide design, efficient statistics, or interpretation. Here, we show that the clustering of correlated DNA methylation at CpGs was similar to that of linkage-disequilibrium (LD) correlation in genetic SNP variation but...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 24656863
DOI: 10.1016/j.ajhg.2014.02.011
PMCID: PMC3980524

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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