Article
The genetic background of generalized pustular psoriasis: IL36RN mutations and CARD14 gain-of-function variants.
Journal of dermatological science - 1 Jun 2014
Sugiura Kazumitsu
Abstract excerpt
Generalized pustular psoriasis (GPP) is often present in patients with existing or prior psoriasis vulgaris (PV; "GPP with PV"). However, cases of GPP have been known to arise without a history of PV ("GPP alone"). There has long been debate over whether GPP alone and GPP with PV are distinct subtypes that are etiologically different from each other. We recently reported that the majority of GPP alone cases is...
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