Article
Correlation of IL36RN and CARD14 mutations with clinical manifestations and laboratory findings in patients with generalised pustular psoriasis.
Indian journal of dermatology, venereology and leprology - 1 Jan 2000
Trai Nguyen Ngoc, Van Em Dang, Van Bui Thi, My Le Huyen, Van Tro Chau, Hao Nguyen Trong, Vu Hoang Anh, Tram Duong Bich, Van Thuong Nguyen, Doanh Le Huu
Abstract excerpt
Background Generalized pustular psoriasis (GPP) is a chronic disease associated with genetic factors related to mutations of the interleukin 36 receptor antagonist gene (IL36RN) and the caspase recruitment domain 14 gene (CARD14). However, the relevance of these mutations to the clinical features and severity of GPP remains unclear. Aims Our objective was to correlate the presence of IL36RN and CARD14 mutations...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.