Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Analysis of growth factor signaling in genetically diverse breast cancer lines

21 Mar 2014

Abstract excerpt

BACKGROUND: Soluble growth factors present in the microenvironment play a major role in tumor development, invasion, metastasis, and responsiveness to targeted therapies. While the biochemistry of growth factor-dependent signal transduction has been studied extensively in individual cell types, relatively little systematic data are available across genetically diverse cell lines. RESULTS: We describe a...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cytokine Signaling Pathways and Interactions
Share to PI3K/AKT/mTOR signaling in cancer
Share to TGF-β signaling in diseases

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 24655548
DOI: 10.1186/1741-7007-12-20

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Analysis of growth factor signaling in genetically diverse breast cancer linesPMID 24655548Read ↗

HER2+ Cancer Cell Dependence on PI3K vs. MAPK Signaling Axes Is Determined by Expression of EGFR, ERBB3 and CDKN1B.Semantic proximity Read ↗

Profiles of Basal and stimulated receptor signaling networks predict drug response in breast cancer lines.Semantic proximity Read ↗

Growth Factor-specific Signaling Pathway Stimulation and Gene Expression Mediated by ErbB ReceptorsSemantic proximity Read ↗

HER/ErbB receptor interactions and signaling patterns in human mammary epithelial cellsSemantic proximity Read ↗

Receptor tyrosine kinases (RTKs) in breast cancer: signaling, therapeutic implications and challengesSemantic proximity Read ↗

Common pathways and functional profiles reveal underlying patterns in Breast, Kidney and Lung cancersSemantic proximity Read ↗

Selective impact of ALK and MELK inhibition on ERα stability and cell proliferation in cell lines representing distinct molecular phenotypes of breast cancer.Semantic proximity Read ↗

Evaluation of FGFR targeting in breast cancer through interrogation of patient-derived models.Semantic proximity Read ↗

The diverse signaling network of EGFR, HER2, HER3 and HER4 tyrosine kinase receptors and the consequences for therapeutic approaches.Semantic proximity Read ↗

Associations with growth factor genes (FGF1, FGF2, PDGFB, FGFR2, NRG2, EGF, ERBB2) with breast cancer risk and survival: the Breast Cancer Health Disparities Study.Semantic proximity Read ↗

Erbb4 and its isoforms: selective regulation of growth factor responses by naturally occurring receptor variants.Semantic proximity Read ↗

Predicting ligand-dependent tumors from multi-dimensional signaling featuresSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.