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Article

HER/ErbB receptor interactions and signaling patterns in human mammary epithelial cells

31 Oct 2009

Abstract excerpt

BACKGROUND: Knowledge about signaling pathways is typically compiled based on data gathered using different cell lines. This approach implicitly assumes that the cell line dependence is not important. However, different cell lines do not always respond to a particular stimulus in the same way, and lack of coherent data collected from closely related cellular systems can be detrimental to the efforts to understand...

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PMID: 19878579
DOI: 10.1186/1471-2121-10-78

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