Article
Analysis of clinical indexes and RUNX3, TBKBP1, PPARGC1B polymorphisms in Chinese Han patients with ankylosing spondylitis.
Genetic testing and molecular biomarkers - 1 Jan 2015
Liu Jun, Lian Zijian, Xiao Yu, Shi Lewis L, Chai Wei, Wang Yan
Abstract excerpt
BACKGROUND: Ankylosing spondylitis (AS) is a genetically determined disease. Runt-related transcription factor 3 (RUNX3), tumor necrosis factor family member-associated NF-κB activator binding kinase 1 binding protein (TBKBP1), and peroxisome proliferator-activated receptor-gamma coactivator 1 beta (PPARGC1B) have recently been found to be associated with susceptibility to AS in patients of Western European...
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