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Article

Gene-based GWAS and biological pathway analysis of the resilience of executive functioning.

Brain imaging and behavior - 1 Mar 2014

Mukherjee Shubhabrata, Kim Sungeun, Ramanan Vijay K, Gibbons Laura E, Nho Kwangsik, Glymour M Maria, Ertekin-Taner Nilüfer, Montine Thomas J, Saykin Andrew J, Crane Paul K

Abstract excerpt

Resilience in executive functioning (EF) is characterized by high EF measured by neuropsychological test performance despite structural brain damage from neurodegenerative conditions. We previously reported single nucleotide polymorphism (SNP) genome-wide association study (GWAS) results for EF resilience. Here, we report gene- and pathway-based analyses of the same resilience phenotype, using an optimal SNP-set...

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Identifiers

PMID: 24072271
DOI: 10.1007/s11682-013-9259-7
PMCID: PMC3944472

Genes

RNASE13

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