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Article

Within-Host Evolution Results in Antigenically Distinct GII.4 Noroviruses

20 Mar 2014

Abstract excerpt

UNLABELLED: Genogroup II, genotype 4 (GII.4) noroviruses are known to rapidly evolve, with the emergence of a new primary strain every 2 to 4 years as herd immunity to the previously circulating strain is overcome. Because viral genetic diversity is higher in chronic than in acute infection, chronically infected immunocompromised people have been hypothesized to be a potential source for new epidemic GII.4...

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PMID: 24648459
DOI: 10.1128/jvi.00203-14

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